This large, adequately powered study provides evidence of decreased odds of depression among current users of A P and decreased odds of anxiety, stress- related disorders, and psychosis combined outcome among past users, and it found no evidence of an increase in anxiety, stress- related disorders, or psychosis combined outcome, depression, epilepsy, or peripheral neuropathy associated with A P use for malaria prophylaxis in travelers when assessing current use or past use and follow- up for 18 months compared with people who did not use antimalarials.
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